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the body converts it before use

Depression-like behaviors were elicited, and the adolescent rats received either Ashwagandha (50 mg/kg/day) or sertraline (5.0 mg/kg/day) as treatment

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The solution is injected, and the needle is withdrawn

In male rats exposed to electric foot shocks, levels of TRP, KYN, 3-HK, and KYNA shift dramatically across plasma and multiple brain regions, normalizing within 24 h suggesting a dynamic and time-sensitive response of KP metabolism to stress [69]