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Notably, enzymes governing polyamine biosynthesis, including glutamic oxaloacetic transaminase 2 (GOT2), aminoacylase-1 (ACY1), ODC, and SDS, exhibit overexpression in prostate cancer, while ornithine aminotransferase (OAT) demonstrates insufficient expression (66)

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86 It has fewer side effects than penicillamine and is effective in dogs with hemolytic anemia caused by copper release from necrotic hepatocytes

Farzad Kakaee, Tabriz University of Medical Sciences, Iran Updates Copyright 2023 Cai, Li, Yang, Luo, Luo, Xiong, He, Chen, Mou, Hu, Yang, Lan and Liu

doi: 10.1016/j.semcancer.2022.02.012