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CRC cells overexpress glucose transporters (e.g., GLUT1) to facilitate massive glucose uptake, preferentially undergoing glycolysis over oxidative phosphorylation even under normoxia, resulting in substantial lactate production

Belly fat is a different animal entirely

The mucus build up in the CF lung can lead to an ideal environment for bacterial growth and makes clearance by immune cells or antibiotics difficult [7]

Due to the emerging role of NAD homeostasis in aging and age-related diseases, our discovery of the role of CD38 in the control of cellular NAD levels opens the possibility that CD38 inhibition may be used as a therapeutic approach to increase cellular NAD levels (Figure 1)[1-4, 6]

B In vivo 03