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However, certain SBA, such as hydroxydeoxycholic acid (HDCA), may partially counteract these effects by modulating gut microbiota composition and activating FXR to regulate lipid metabolism genes [65]

Dihexa acetate is one of them

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Here, we find that SUMOylation of TDP-43 occurs at K408 by SUMO2/3 in response to stress

High-fat diet promotes colorectal tumorigenesis through modulating gut microbiota and metabolites