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36 The incidence of DILI due to ICI was reported to be 0.814.6% for the CTLA-4 inhibitor ipilimumab and 2.716% for PD-1/PD-L1 inhibitors such as nivolumab

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Moreover, fungi stand out among eukaryotes due to their potent impact on the host immune system, exerting diverse immunological effects (32)

doi: 10.1523/JNEUROSCI.15-02-01384.1995