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Recent studies have illustrated the role of the SIRT1-Nrf2-HO-1 pathway in the regulation of ferroptosis

Ann Oncol 20:736740 Monk B, Kauderer J, Moxley K, Bonebrake AJ, Dewdney SB, Secord AA, Ueland FR, Johnston CM, Aghajanian C (2018) A phase II evaluation of elesclomol sodium and weekly paclitaxel in the treatment of recurrent or persistent platinum-resistant ovarian, fallopian tube or primary peritoneal cancer: an NRG oncology/gynecologic oncology group study

However, a recent systematic evaluation of preclinical models demonstrated that stimulating (rather than inhibiting) fatty acid oxidation improves cardiac function 55

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