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The apoptosis inhibiting protein, XIAP is highly expressed in myeloid leukemic cells, regulated by ATRA and cytokines, and cleaved by caspases

Ir J Med Sci 192 , 12411247 (2023)

This dual-agonist strategy leverages complementary mechanisms: Cagrilintides amylin receptor activity pairs with semaglutides GLP-1 receptor agonism to produce additive or synergistic weight loss and metabolic benefits