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Immunoblot assays Cell lysates from HCC-1806, PC3 WT and PC3 GGT1 + cells were obtained by placing PBS-washed cell plates on ice and scraping with RIPA buffer (Thermo Scientific, 89900) containing Halt Protease and Phosphatase Inhibitor cocktail (Thermo Scientific, 1861280)

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We obtained comparable signatures using mSigHdp, a signature extraction method that uses a hierarchical Dirichlet process model (HDP) 38,39 (Supplementary Fig

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Do not apply to irritated or damaged skin