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The inoculum for infection was prepared by diluting stock vials as described previously ( Aerosol Infection of Mice, Treatment, and Bacterial CFU Assay The diabetic C57BL db/db mice of 68 weeks old were purchased from Jackson Laboratories (Bar Harbor, ME, United States)

Zaha, I., Muresan, M., Tulcan, C., Huniadi, A., Naghi, P., Sandor, M., Tripon, R., Gaspar, C., Klaudia-Melinda, M., Sachelarie, L., & Stefan, L

niaaa.nih.gov Widmark, E.M.P

Synthesizing these findings, CBD regulates macrophage polarization by reducing pro-inflammatory M1 phenotypes, affecting TNF- secretion, and inhibiting NO production through eNOS/iNOS pathways