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Description

J Exp Med 192:23748

Oncologist 7 , 288323 (2002)

Nature 420 , 860867 (2002)

D., Hellmann M., Woo K., et al

Since active compounds produce a decrease in signal in the primary assay, confirmation was required that the reduction in luminescence was not a result of general cytotoxicity by the compound or by inhibition of luciferase itself