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The first two Technical Notes were issued in April and July with an update on works concluded to date and work re-sequenced due to external factors

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Class II: Includes medial and lateral depressionoften involves nasojugal and palpebromalar grooves

Immunohistochemical staining using anti aminopeptidase A, a specific marker of renal proximal tubular cells 36 , revealed extensive destruction of these cells in the Tm-treated WT kidneys but not in the Mgst2 -deficient kidneys (Fig