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Description

Its transcription is regulated by NRF2 and system X c inhibition

In addition, the intracellular GSH pool is normally very large (6591 M in our model, see Table 1)

Parkin promotes proteasomal degradation of p62: Implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease

With the advent of anti-amyloid monoclonal antibodies (mAbs), agents such as aducanumab, lecanemab, and donanemab have shown therapeutic benefits in clinical trials (van Dyck et al., 2023