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Name: on glutathione sepharose 4b ge healthcare Life Sciences 17-0756-05 4B, 100mL Glutathione Sepharose 4B GST glutathione sepharose dtt Resin carbon
Brand: metalmesh.com.au
SKU: 54134869937
Price: 20.67 USD
Availability: InStock
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Description

Upon binding to cytoplasmic glucocorticoid receptors (GR), corticosteroids induce translocation of GR complexes into the nucleus, where they interact with glucocorticoid response elements (GREs) to upregulate anti-inflammatory genes (e.g., IL-10, DUSP-1) and suppress pro-inflammatory mediators like IL-1, IL-6, TNF-, and chemokines, such as MCP-1 and IL-8 (McManus 2003