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cAMP-activated Ca 2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways

The excessive production of 5oxoproline exceeds the capacity of 5oxoprolinase, and 5oxoproline accumulates in the body fluids, leading to metabolic acidosis and 5oxoprolinuria (Meister and Larsson, 1995)

It is useful if you are travelling as it avoids having to take multiple containers

Villarreal-Reyna G, Garza-Morales R, Soto-Dominguez A, Montanez-Guerrero L, Saucedo-Cardenas O, Gomez-Flores M

Zhou M, Ma X, Zhang J, Lu X (2024) 3,5-Dimethyl-8-methoxy-3,4-dihydro-1H-isochromen-6-ol Attenuates Ulcerative Colitis via Targeting NLRP3 in Mice