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Nitric oxide is the endothelial factor responsible for relaxation of smooth musculature surrounding the arterials and the pre-capillary sphincters thereby producing vasodilation and increased blood flow into the capillary bed of the exercising muscle tissue

Under physiological conditions, LCACs have the capacity to regulate the current amplitude and kinetics of hERG channels in the heart, which have important effects on arrhythmia [121]

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Martinotti, G., Andreoli, S., Reina, D., Di, Nicola M., Ortolani, I., Tedeschi, D., Fanella, F., Pozzi, G., Iannoni, E., D'Iddio, S., and Prof, L

Necrotizing enterocolitis leads to disruption of tight junctions and increase in gut permeability in a mouse model