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In some embodiments, the present invention can be used to classify a sample (e.g., from a subject) that is involved in or does not respond to or is at risk for a cancer therapy (e.g., at least one modulator of a biomarker listed in table 1 and/or table 2) using statistical algorithms and/or empirical data (e.g., the amount or activity of at least one target listed in table 1 and/or table 2)

Hong, S., Kim, S., Kim, K

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When we do, it will be within a supervised clinical framework