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As you have an idea about the negative implications of manmade activities on global warming

Although cigarette smoke is very complex, consisting of over 4,000 compounds linked to CVD, most studies suggest that carbon monoxide, reactive oxygen species, and nicotine are responsible for the pathogenesis of smoking-induced cardiovascular disorders ( 10 , 11 )

Moody, Hani M.Mahmoud-Elsayed, Jonathan Senior, Uzma Gul, Ayisha M Khan-Kheil, Sebastian Horne, Amitava Banerjee, William M Bradlow, Robert Huggett, Sandeep S Hothi, Muhammad Shahid, Richard P Steeds