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Metformin and vitamin B 12 deficiency Metformin-induced vitamin B 12 deficiency was reported as early as 1971 when Tomkin et al

It is a natural antioxidant found in spinach, asparagus, avocado, etc

The addition of the ROS scavenger, N-acetyl cysteine, significantly rescued PS127 family-induced cytotoxicity, indicating that AML cells are sensitive to increases in ROS

The main source of energy for podocytes is glucose metabolism, with both the anaerobic glycolytic pathway and mitochondrial OXPHOS providing energy for mature podocytes [59]

Front Nutr 4:76 Brown DR et al (2018) Astaxanthin in exercise metabolism, performance and recovery: a review