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The SELECT trial enrolled over 17,000 participants with established cardiovascular disease and obesity (without diabetes) and followed them for a median of approximately 40 months

[DOI] [PubMed] [Google Scholar] 36.Laron Z., Halberstadt B.E

Urinary methylmalonic acid as an indicator of early vitamin B12 deficiency and its role in polyneuropathy in type 2 diabetes

People with the following should discuss risks carefully with a medical professional: Liver disease Kidney disease Pernicious anemia Known allergies to any ingredient in the formulation Pregnancy or breastfeeding (safety not well-studied avoid unless prescribed) Because ingredients differ between providers, always verify the formulation and follow prescribed dosing to minimize risk

Disposal of used vials and syringes follows standard sharps safety protocols