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Lowered GSH levels may be relevant to bipolar pathophysiology in more severely ill patients, particular those with significant current mood disturbance

Glutamate immunoreactivity in the cat retina: a quantitative study

The rationale involves complementary mechanisms

Enhancements of dopamine bio-synthesis as estimated fi'om HVA concentration in CSF correlate withCSF tyrosine (C), Increases in the biosynthesis of dopamine and serotonin as measured by increased CSF concentrations of HVA and5-HIAA correlate with dietary tyrosine supplement (D)

This receptor-level confrontation operates as a molecular switch: PYL binding stabilizes RGL2 through dual mechanismsdirect interaction and functional sequestration of DWA1, the substrate receptor for E3 ubiquitin ligase