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Understanding the ramifications of this perception change represents a critical consideration when developing cessation strategies, said David Gerber, M.D., Professor of Internal Medicine and in the Peter ODonnell Jr

Investigations reviewed here assessed whether switching to e-cigarettes present less risk than smoking: 1) compare the constituents of the aerosol from e-cigarettes to cigarette smoke, 2) examine the toxicity of aerosols in vitro using tissue culture approaches and in vivo using animal studies, 3) measure HPHC levels in blood and urine from individuals who switch to e-cigarettes and compare them with values in adult smokers, and 4) compare clinical biomarkers of exposure that are known risk factors for smoking-related diseases in individuals who switch to e-cigarettes and those who continue to smoke cigarettes

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